The Chemistry Files este cel de-al 4-lea mixtape al lui The Alchemist și a fost lansat în anul 2006, prin ALC Records.
TRACKLIST:
| 1 | –Eminem | Em Speaks |
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| 2 | –The Alchemist | Reppin' ALC |
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| 3 | –Mobb Deep | The Infamous |
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| 4 | –Cam'ron | Wet Wipes |
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| 5 | –Scarface + The Product |
G-Type |
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| 6 | –Mobb Deep | Poppin' Bottles |
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| 7 | –Bobby Creekwater | All I Do |
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| 8 | –The Alchemist | We Got This |
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| 9 | –AZ | Professional Style |
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| 10 | –Obie Trice | I'm Back |
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| 11 | –B-Real | Body Something |
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| 12 | –Prodigy | What's Poppin' Thun |
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| 13 | –Havoc | Fall Back |
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| 14 | –The Alchemist | That's That |
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| 15 | –Tony Yayo | Gunz Is Razors |
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| 16 | –Mobb Deep + The Alchemist | What's The Word |
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| 17 | –40 Glocc + Prodigy | When You're Dying |
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| 18 | –Poet | Bloody Mess |
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- Phonographic Copyright (p) – ALC Records
- Copyright (c) – ALC Records
- Artwork, Design – Dom Dirtee
- Producer – The Alchemist (tracks: 1 to 15, 17, 18), Havoc (tracks: 16)
Issued in a Digipak.